沈爱国
沈爱国,博士、副教授,武汉大学化学与分子科学学院 副教授,博士生导师,中国物理学会光散射专业委员会委员,湖北省化学化工学会谱学专业委员会秘书长。2006年7月毕业于武汉大学化学与分子科学学院分析化学专业,获博士学位(导师:胡继明教授)。毕业后留校任教并连续3年赴德国不来梅Jacobs大学和韩国全南大学开展国际合作研究(每年3-4个月)。2008年12月晋升为副教授,2010年被遴选为博士生导师。2011年6月至2012年6月获德国DAAD-王宽诚博士后奖学金,在德国图宾根大学物理与理论化学所从事针尖增强拉曼光谱的合作研究(合作导师:Prof. Alfred J. Meixner)。现主要从事拉曼光谱的生化传感、生物成像及仪器研制等领域的研究工作。先后主持1项国家重大科学仪器设备开发项目,3项国家自然科学基金项目,1项中石油科技创新项目和2项国家重点实验室开放基金项目;参与1项国家自然科学基金仪器专项重点项目和1项国家重大研究计划培育项目。迄今已在Advanced Functional Materials、Analytical 化学、Journal of Materials Chemistry、Chemical Communications、Biosensors \u0026 Bioelectronics、Bioconjugate Chemistry等杂志上发表SCI源刊论文60余篇。
人物履历
2008.12- 武汉大学化学与分子科学学院 副教授(被遴选为分析化学(2010.07)和材料学专业(2012.06)博士生指导教师)
2011.06-2012.06德国蒂宾根大学物理化学与理论化学研究所 访问学者
2006.07-2008.11 武汉大学化学与分子科学学院 讲师(期间连续三年(3-4月/年)赴德国不来梅Jacobs大学和韩国全南大学从事国际合作研究)
2001.09-2006.07 武汉大学化学与分子科学学院 分析化学 博士
1997.09-2001.06湖北大学化学与材料科学学院 化学教育 学士
主授课程
研究生专业课程:《激光分析》
通识课程:《近代化学发展史》与《人文化学》
实验课程:《仪器分析实验》(红外&拉曼)
学术兼职
中国物理学会光散射专业委员会委员
Journal of Raman Spectroscopy等期刊审稿人
研究领域
生物拉曼光谱分析与仪器研制
纳米材料与成像分析
科研项目
1、国家重大科学仪器设备开发专项子项目,2012YQ16000701、激光拉曼光谱气体分析仪的研制、2012/10-2015/09、218万元、在研、主持
2、国家自然科学基金面上项目,21175101、原位、活体检测植物激素的SERS探针新技术、2011/01-2014/12、60万、在研、主持
3、国家自然科学基金青年科学基金项目,20705025、新型复合拉曼探针用于胃癌早期诊断的研究、2008/01-2010/12、20万、已结题、主持
4、中国石油科技创新基金项目,改善二氧化碳驱油关键技术研究、2008/06-2010/12、20万、已结题、主持
5、国家自然科学基金面上项目,41273093、气藏相关的特异性甲氧化菌的拉曼光谱研究及其在天然气气藏现场、快速勘探中的应用、2013/01-2016/12、90万、在研、参加
6、国家自然科学基金仪器专项重点项目,20927003、上消化道癌症原位早期诊断激光拉曼光谱系统的研制、2010/01-2012/12、150万,在研、参加
7、国家自然科学基金重大研究计划培育项目,90913013 、活细胞组分及其相互作用的靶向表面增强拉曼光谱探针技术研究、2008/06-2010/12、50万、已结题、参加。
代表性论文
1. Wei Fang, Xin-Wei Zhang, Yong Chen, Liang Wan, Wei-Hua Huang,Ai-Guo Shen, Ji-Ming Hu, Portable SERS-enabled micropipettes for microarea sampling and reliably quantitative detection of surface organic residues,Analytical Chemistry, 2015, ASAP
2. Jun-Rong Li,Guan-Nan Zhang, Li-HuaWang,Ai-Guo Shen,Ji-MingHu, Simultaneous enzymatic and SERS properties of bifunctional chitosan-modified popcorn-like Au-Ag nanoparticles for high sensitive detection of melamine in milk powder, Talanta, 2015, 140, 204-211.
3. Yi Zeng, Jin-JuPei,Li-Hua Wang,Ai-Guo Shen,Ji-Ming Hu, A sensitive sequential "on/off" SERS assay for heparin with wider detection window and higher reliability based on the reversed surface charge changes of functionalized Au@Ag nanoparticles, Biosensors and Bioelectronics, 2015, 66, 55-61.
4. Wen-Liang Zha, Ying Cheng,Wei Yu,Xiao-Bin Zhang,Ai-Guo Shen,Ji-Ming Hu, HPLC assisted Raman spectroscopic studies on bladder cancer, Laser Physics Letters, 2015, 12, 045701.
5. Guan-Nan Zhang,Jun-Rong Li,Ai-Guo Shen,Ji-MingHu, Synthesis of size-tunable chitosan encapsulated gold-silver nanoflowers and their application in SERS imaging of living cells, Physical Chemistry Chemical Physics, 2015, 17, 21261-21267.
6. Li-Hua Wang,Yi Zeng,Ai-Guo Shen,Xiao-越南盾 Zhou,Ji-Ming Hu, Three dimensional nano-assemblies of noble metal nanoparticle-INFINITE coordination polymers as specific oxidase mimetics for degradation of methylene 蓝色 without adding any cosubstrate, Chemical Communications, 2015, 51, 2052-2055.
7. Man-Man Lin,Ai-Guo Shen,Hui-Lu Yao,Zhi-Zhi Zhang,Ji-Ming Hu, Real-时间 molecular profiling of photochemically induced rat thrombosis in vivo through quantitative Raman analysis of blood, Laser Physics Letters, 2014, 11, 115607.
8. Gan Qu,Guan-Nan Zhang,Zi-Tong Wu,Ai-Guo Shen,Jian-Bo Wang,Ji-Ming Hu, A "turn-off" SERS assay of 肝素 with high selectivity based on heparin-peptide complex and Raman labelled gold nanoparticles, Biosensors and Bioelectronics, 2014, 60, 124-129.
9. Gan Qu,Guan-Nan Zhang,Yan Su,Hui-Chun Xu,Xiao-Dong Zhou,Ai-Guo Shen,Ji-Ming Hu, A Label-free and Separation-free Detection for 三聚氰胺 Based on Surface Enhanced Raman Scattering, Chinese Journal of Analytical Chemistry, 2014, 42, 1022-1027.
10. Li-Hua Wang,Ai-Guo Shen,Xian-Chang Li,Yi Zeng,Xiao-越南盾 Zhou,Ryan MRichards, Ji-Ming Hu, Inclusion of guest materials in aqueous coordination network shells spontaneously generated by reacting 2,5-dimercapto-1,3,4-thiadiazole with nanoscale metallic silver, RSC Advances, 2014, 4, 34294-34302.
11. Zi-Tong Wu,Yi-Zhen Liu,Xiao-越南盾 Zhou,Ai-Guo Shen,Ji-Ming Hu, A "turn-off" SERS-based detection Platform for ultra sensitive detection of thrombin based on enzymatic assays, Biosensors and Bioelectronics, 2013, 44, 10-15.
12. Le Su, Yong Chen, Guan-Nan Zhang, Li-Hua Wang,Ai-Guo Shen, Xiao-越南盾 Zhou, Xiao-Hua Wang, Ji-Ming Hu,In vivoandin situmonitoring of the nitric oxide stimulus response of single cancer cells by Raman spectroscopy, Laser Physics Letters, 2013, 10, 045608.
13. Wei-Song Yi,Dian-Sheng Cui, ZhiLi,Lan-Lan Wu,Ai-Guo Shen,Ji-Ming Hu,Gastric cancer differentiation using Fourier transform near-infrared spectroscopy with unsupervised pattern recognition, Spectrochimica Acta Part A, 2013, 101, 127-131.
14. Guan-Nan Zhang, Gan Qu, Yong Chen,Ai-Guo Shen, Wei Xie, Xiao-越南盾 Zhou, Ji-Ming Hu, Controlling carbon encapsulation of gold nano-aggregates as highly sensitive and spectrally stable SERS tags for live cell imaging,Journal of Materials 化学 B, 2013, 1, 4364-4369.
15.Ai-Guo Shen, Jin Peng, Qing-Hong Zhao, Le Su, Xiao-Hua Wang, Ji-Ming Hu*, Qing Yang*, Accurate and noninvasive embryos screening during in vitro fertilization (IVF) assisted by Raman analysis of embryos culture medium, Laser Physics Letters, 2012, 9, 322-328.
16. Pu Chen, Yong Chen, Le Su,Ai-Guo Shen, Jun-Cheng Hu, Xiao-Hua Wang, Ji-Ming Hu,β-Carotene doped silica nanoparticles as a novel resonance Raman scattering tag forin vivocellular imaging, Journal of Materials 化学, 2012, 22, 631-635.
17.Ai-Guo Shen, Jing-Zhe Guo, Wei Xie, Meng-Xiang Sun,Ryan M Richards, Ji-Ming Hu, surfaceenhanced Raman spectroscopy in living 植物界 using triplex Au-Ag-C core–shell nanoparticles,Journal of Raman Spectroscopy, 2011, 42, 879-884.
18.Ai-Guo Shen, Li-Fang Chen, Wei Xie, Jun-Cheng Hu, Ao Zeng, Ryan M Richards, Ji-Ming Hu, Triplex Au-Ag-C core-shell nanoparticles as a novel Raman labels, Advanced Functional Materials, 2010, 20, 969-975
荣誉获奖
2005年10月获第十三届全国光散射学术会议优秀青年论文奖